Does CBD Balm Help Arthritis Pain? – What Joe Rogan and Science Say

Introduction

People living with arthritis often search for natural alternatives to non‑steroidal anti‑inflammatory drugs (NSAIDs). CBD balms have become increasingly popular, but do they really work for arthritis?  On a February 2021 episode of the Joe Rogan Experience, Joe Rogan told Elon Musk that CBD “works great for people with arthritis and people with sore muscles” and that it provides relief without psychoactive effects. His comment echoes anecdotal reports from users, but it also raises an important question: what does the science actually say?

How topical CBD works

CBD (cannabidiol) interacts with the body’s endocannabinoid system, which regulates pain, inflammation and immune responses. CB₁ and CB₂ receptors are found in skin cells and immune cells. By applying a CBD balm directly to the skin, cannabinoids may influence these receptors in the local area without entering the bloodstream.

Evidence from animal studies

There are currently few high‑quality human trials for topical CBD in arthritis; however, a notable 2016 study used a rat model of adjuvant‑induced arthritis. Researchers applied CBD gel (0.6–62 mg/day) to arthritic rats for four days. The transdermal CBD significantly reduced joint swelling, spontaneous pain scores and immune‑cell infiltration, and improved pain‑withdrawal thresholds compared with controls. The study concluded that topical CBD has “therapeutic potential for relief of arthritis pain‑related behaviors and inflammation without evident side‑effects” .

Limited clinical evidence

So far, there are no large randomized controlled trials of CBD balms in human arthritis. One anonymous questionnaire study suggested that CBD use was associated with perceived improvement in arthritis‑related joint pain and sleep. However, self‑reported data can be biased, and more rigorous human trials are needed.

Joe Rogan’s experience and POWER BALM

Joe Rogan’s casual endorsement (“CBD works great for people with arthritis and sore muscles” ) reflects many users’ anecdotal experiences. POWER BALM™ is formulated with full‑spectrum hemp extract, arnica and peppermint oil. Many customers report that massaging it into sore joints brings rapid soothing and warmth. Although such testimonials cannot replace clinical trials, they align with the mechanistic evidence that cannabinoids can reduce inflammation and nociceptive signalling .

Bottom line

Topical CBD balms like POWER BALM™ show promise for managing arthritis symptoms, and even high‑profile podcasters like Joe Rogan believe they work. Animal studies demonstrate significant reductions in inflammation and pain , but human evidence remains limited. If you try a CBD balm, look for third‑party test results (COAs) and speak to a healthcare professional before making major changes to your treatment plan.

Try POWER BALM™ on your arthritis today

GAME UP® POWER BALM™ is an All-Natural Mentholated Ultra Strength CBD Pain Balm that delivers professional grade relief with a powerful 9200mg dose of premium organic hemp CBD isolate infused with our signature blend of coconut oil, beeswax, menthol and other natural ingredients.