What is CBG (cannabigerol)?
Cannabigerol (CBG) is a lesser-known cannabinoid that only recently started getting worldwide acknowledgment for its host of interesting and beneficial properties.
CBG is considered a minor cannabinoid because it is present in low levels (usually less than 1%) in most cannabis strains. Cannabis plants produce cannabigerolic acid (CBGA), the precursor to the three main cannabinoid lines: tetrahydrocannabinolic acid (THCA), cannabidiolic acid (CBDA), and cannabichromenic acid (CBCA).
Specific enzymes in the plant break CBGA down and “direct” it toward one of the three lines. The acids are exposed to ultraviolet light or heat, and voila, they become the cannabinoids we know: THC and CBD. In most strains, CBGA is immediately converted to either THCA or CBDA. Thus, more THC means less CBG and CBD (and vice versa) by nature of how these compounds are synthesized.
To obtain higher yields of CBG, breeders are experimenting with genetic manipulation and cross-breeding of plants.
CBG’s potential medical benefits
The human body’s built-in endocannabinoid system works to keep the body in its balanced state of homeostasis. While there are specific details about how cannabinoids work, in general the endocannabinoid system performs different functions specific to each area of the body. For example, at an injury site, the ECS can help regulate immune cells to limit inflammation.
CBG has been found to act on very specific physiological systems and problems, and results for medicinal use are promising:
- Endocannabinoid receptors are prevalent in eye structures, and interestingly, CBG is thought to be particularly effective in treating glaucoma because it reduces intraocular pressure. It is a powerful vasodilator and has neuroprotective effects to boot.
- In animal experiments involving mice, CBG was found to be effective in decreasing the inflammation characteristic of inflammatory bowel disease.
- In a recent 2015 study, CBG was shown to protect neurons in mice with Huntington’s disease, which is characterized by nerve cell degeneration in the brain.
- CBG is showing great promise as a cancer fighter. Specifically, CBG was shown to block receptors that cause cancer cell growth. In one such study, it was shown to inhibit the growth of colorectal cancer cells in mice, thereby slowing colon cancer growth. CBG inhibited tumors and chemically-induced colon carcinogenesis, therefore demonstrating a very exciting possibility for a cure for colorectal cancer.
- European research shows evidence that CBG is an effective antibacterial agent, particularly against methicillin-resistant Staphylococcus aureus (MRSA) microbial strains resistant to several classes of drugs. Since the 1950s, topical formulations of cannabis have been effective in skin infections, but researchers at the time were unaware of the plant’s chemical composition.
- In a very recent 2017 study, researchers showed that a form of CBG purified to remove delta-9 THC was a very effective appetite stimulant in rats. This may lead to a novel non-psychotropic therapeutic option for cachexia, the muscle wasting and severe weight loss seen in late stage cancer and other diseases.
- In a study that looked at the effects of five different cannabinoids on bladder contractions, CBG tested best at inhibiting muscle contractions, so it may be a future tool in preventing bladder dysfunction disorders.
Scientists are excited about these initial CBG results and are promoting future research with CBG alone or CBG in combination with other cannabinoids and therapies for the treatment of multiple maladies. Because it is non-psychotropic, CBG has a promising wide range of potential applications not only for the problems mentioned above, but also as an analgesic, therapy for psoriasis, and as an antidepressant.
Looking to give CBG a try? View all our CBG products and see which one is best for you.
WHITE CBG HEMP FLOWER
White CBG hemp flower contains 12 to 14% CBG with frosty, silver trichomes covering the bright green hemp buds. This CBG-rich hemp strain offers a citrusy and hoppy aroma with hints of chamomile and piney fresh mountain air.
CBG stands for cannabigerolic acid which is the seeds converted into tetrahydrocannabinolic acid (THCA), the precursor of tetrahydrocannabinol (THC), and cannabidiolic acid (CBDA). Most hemp strains contain only small amounts of CBG, but new CBG-rich hemp strains are now available. Because CBG hemp flower is still a less common variety, it often comes at a higher cost.
CBG is the parent molecule of THC and CBD, which have different molecular structures and different interactions with the endocannabinoid system. Unlike THC, CBD and CBG are non-psychoactive, meaning they won’t get you high. Our CBG hemp flower contains less than 0.3% delta-9-THC.
With initial smells of fresh plant matter, cypress, and a bit of spicy skunk, this strain’s flavors intensify and evolve when broken up, shifting to a bouquet that includes hints of cilantro and gas.
CBG has been found to fight inflammation, pain, nausea and research has shown it works to slow the proliferation of cancer cells as well as significantly reduces intraocular eye pressure caused by glaucoma. CBG shows promise as an antibacterial agent and an anti-inflammatory as well.